Brand Name Manufacturers |
Androcur by Schering AG, Farma (Germany)
Cyproteron by NM Pharma (England) |
Generic Manufacturers |
? |
Pharmacology |
Androgen receptor antagonist. Weak gonadal androgen production
inhibitor. Weak progesterone. |
Delivery |
10mg, 50mg oral tablets |
Typical dosage |
Pre-op 10mg/wk-100mg/day (See comment below)
Post-op not recommended |
Availability |
Not approved by U.S. FDA |
Indications |
Acne and/or overactive oil glands. Androgen dependent loss
of scalp hair. Hirsutism. Inoperable prostate tumors. |
Contraindications |
Lactation. Dubin-Johnson syndrome. Liver disease or tumor.
Previous or existing blood clotting disorder. Rotor syndrome.
Severe chronic-depression. Severe diabetes with vascular changes.
Sickle-cell anaemia. Wasting diseases (with the exception
of prostate tumor). |
Adverse reactions |
- CNS
-
Headache. Lessened ability to concentrate. Mental depression.
Tiredness.
- Gastrointestinal
-
Nausea.
- Other
-
Blood clotting disorders. Carbohydrate metabolism changes.
Liver dysfunction or tumors. Shortness of breath.
|
Comments |
The extreme range of dosage comes from input that some people
find 10mg/wk sufficient to induce total impotence, and yet
others take as much as 200mg/day with no obvious short-term
adverse effects. Given this range, it would seem prudent
to start on the low side and work your way up only if necessary.
More than 100mg/day is generally considered excessive.
Also,
do not confuse with the antibiotic named "Cipro." |
Additional
Info: |
CCO
Formulary Data Sheet on Androcur (PDF file on this site) |